The daughter of law clerk John Andrew Murdoch and his wife Rebecca (Murphy), Nina grew up in the small town of Woodburn, NSW. She attended the Sydney Girls' High School from 1904 until 1907, and then taught at the Sydney Boys' Preparatory School.
Nina began writing poetry whilst still at high school and published many of her poems in The Bulletin between 1913 - 1922. In 1913 she won the Bulletin prize for a sonnet about Canberra. She worked for the Sydney Sun and became one of the first women general reporters. She married in 1917.
Nina died in 1976.